Abstract: Multicellularity emerges from the ability of cells to undergo functional differentiation. One of the key mechanisms that enables this coordination is cellular signalling—a series of molecular interactions within or between cells that induce changes in cell behaviour or gene … Read More
Abstract: Fluconazole (FLU) is a widely used antifungal agent frequently detected in surface waters because of its extensive use in medicine, agriculture, and personal care products. Despite concerns about its persistence and developmental toxicity in aquatic species, its effects on … Read More
Abstract: The PRICKLE proteins (PRICKLE1-PRICKLE4) play essential roles in the WNT/planar cell polarity (WNT/PCP) pathway in vertebrates. This signaling system governs cell polarity, tissue architecture, and coordinated cell movements, yet the specific roles and molecular mechanisms of individual PRICKLE members … Read More
Abstract: Photorhabdus laumondii is a well-known bacterium with a complex life cycle involving mutualism with nematodes of the genus Heterorhabditis and pathogenicity towards insect hosts. It provides an excellent model for studying the diverse roles of lectins, saccharide-binding proteins, in … Read More
Abstract: Lead nanoparticles (PbNPs) in air pollution pose a significant threat to human health, especially due to their neurotoxic effects. In this study, we exposed mice to lead(II) oxide nanoparticles (PbONPs) in inhalation chambers to mimic real-life exposure and assess … Read More
Highlights NMR can provide information on the nucleic acids‘ structure, dynamics, and interactions in living cells We overview strategies to acquire and present in-cell NMR data on nucleic acids We provide ‘behind-the-scene’ information vital to comprehending the data meaning Abstract … Read More
Highlights Abstract Bee health is influenced by multiple factors, including nutrition, immunity, and parasitic pressures. Since the spread of Varroa destructor, overwintering survival has significantly declined, making it one of the most serious threats to honey bee (Apis mellifera L.) … Read More
Highlights: The study examines H. bacteriophora recovery to active parasitism upon host contact. Host and non-biological stimuli trigger recovery and release of secreted proteins. Secretomes of nematodes responding to various activation materials were identified. Insect materials induce the release of proteins key … Read More
Abstract: Intensive agricultural practices impact the health and nutrition of pollinators like honey bees (Apis mellifera). Rapeseed (Brassica napus L.) is widely cultivated, providing diverse nutrients and phytochemicals, including S-methyl-L-cysteine sulfoxide (SMCSO). While the nutritional impact of rapeseed on bees … Read More
Abstract Actomyosin contractility represents an ancient feature of eukaryotic cells participating in many developmental and homeostasis events, including tissue morphogenesis, muscle contraction and cell migration, with dysregulation implicated in various pathological conditions, such as cancer. At the molecular level, actomyosin … Read More