{"id":8611,"date":"2021-08-04T07:22:45","date_gmt":"2021-08-04T07:22:45","guid":{"rendered":"http:\/\/www.sci.muni.cz\/ofiz\/?p=8611"},"modified":"2021-08-04T07:23:30","modified_gmt":"2021-08-04T07:23:30","slug":"danio-rerio-embryos-in-research-%f0%9f%90%9f","status":"publish","type":"post","link":"https:\/\/ueb1.sci.muni.cz\/ofiz\/en\/danio-rerio-embryos-in-research-%f0%9f%90%9f\/","title":{"rendered":"Danio rerio embryos in research \ud83d\udc1f"},"content":{"rendered":"\n<h5>We are already making full use of the newly accredited <em><strong>Danio rerio<\/strong><\/em> fish farming facility!\u00a0<\/h5>\n<h5><a href=\"https:\/\/www.sci.muni.cz\/ofiz\/en\/bryja\/\">Mgr. Michaela Noskov\u00e1 from the group of prof. Bryja<\/a>\u00a0works with their embryos, into which she will then inject tumor cells. This will allow her to monitor their interactions in the microenvironment of a living organism. Embryos with transplanted tumor cells can then be used, for example, to test the effects of selected therapeutic drugs.<\/h5>\n<h5>In the pictures you can see fish embryos 4 days after fertilization. The darker image shows fish embryos in their natural appearance, while the lighter image shows embryos after application of 1-phenyl 2-thiourea (PTU), which makes the body of the fish embryo transparent (because it blocks melanin production). In transparent embryos, it is then easier to monitor the progression of tumor cells, which can be additionally fluorescently labeled and further monitored under a fluorescence microscope.<\/h5>\n\n\n\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"884\" height=\"661\" src=\"https:\/\/www.sci.muni.cz\/ofiz\/wp-content\/uploads\/2021\/08\/ezgif.com-gif-maker.gif\" alt=\"\" class=\"wp-image-8605\"\/><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>We are already making full use of the newly accredited Danio rerio fish farming facility!\u00a0 Mgr. Michaela Noskov\u00e1 from the group of prof. Bryja\u00a0works with their embryos, into which she will then inject tumor cells. This will allow her to &hellip; <a href=\"https:\/\/ueb1.sci.muni.cz\/ofiz\/en\/danio-rerio-embryos-in-research-%f0%9f%90%9f\/\">Read More<\/a><\/p>\n","protected":false},"author":5,"featured_media":8605,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"kt_blocks_editor_width":"","_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[267],"tags":[],"class_list":["post-8611","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.1.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Danio rerio embryos in research \ud83d\udc1f - Department of Animal Physiology and Immunology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ueb1.sci.muni.cz\/ofiz\/en\/danio-rerio-embryos-in-research-\ud83d\udc1f\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Danio rerio embryos in research \ud83d\udc1f - Department of Animal Physiology and Immunology\" \/>\n<meta property=\"og:description\" content=\"We are already making full use of the newly accredited Danio rerio fish farming facility!\u00a0 Mgr. Michaela Noskov\u00e1 from the group of prof. Bryja\u00a0works with their embryos, into which she will then inject tumor cells. This will allow her to &hellip; Read More\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ueb1.sci.muni.cz\/ofiz\/en\/danio-rerio-embryos-in-research-\ud83d\udc1f\/\" \/>\n<meta property=\"og:site_name\" content=\"Department of Animal Physiology and Immunology\" \/>\n<meta property=\"article:published_time\" content=\"2021-08-04T07:22:45+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2021-08-04T07:23:30+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ueb1.sci.muni.cz\/ofiz\/wp-content\/uploads\/2021\/08\/ezgif.com-gif-maker.gif\" \/>\n\t<meta property=\"og:image:width\" content=\"884\" \/>\n\t<meta property=\"og:image:height\" content=\"661\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/gif\" \/>\n<meta name=\"author\" content=\"Lucie Nesvadbov\u00e1\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Lucie Nesvadbov\u00e1\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/ueb1.sci.muni.cz\/ofiz\/en\/danio-rerio-embryos-in-research-%f0%9f%90%9f\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/ueb1.sci.muni.cz\/ofiz\/en\/danio-rerio-embryos-in-research-%f0%9f%90%9f\/\"},\"author\":{\"name\":\"Lucie Nesvadbov\u00e1\",\"@id\":\"https:\/\/ueb1.sci.muni.cz\/ofiz\/#\/schema\/person\/3119766c8e4c78f08bbbde220469aee6\"},\"headline\":\"Danio rerio embryos in research \ud83d\udc1f\",\"datePublished\":\"2021-08-04T07:22:45+00:00\",\"dateModified\":\"2021-08-04T07:23:30+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/ueb1.sci.muni.cz\/ofiz\/en\/danio-rerio-embryos-in-research-%f0%9f%90%9f\/\"},\"wordCount\":149,\"publisher\":{\"@id\":\"https:\/\/ueb1.sci.muni.cz\/ofiz\/#organization\"},\"image\":{\"@id\":\"https:\/\/ueb1.sci.muni.cz\/ofiz\/en\/danio-rerio-embryos-in-research-%f0%9f%90%9f\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/ueb1.sci.muni.cz\/ofiz\/wp-content\/uploads\/2021\/08\/ezgif.com-gif-maker.gif\",\"articleSection\":[\"News\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/ueb1.sci.muni.cz\/ofiz\/en\/danio-rerio-embryos-in-research-%f0%9f%90%9f\/\",\"url\":\"https:\/\/ueb1.sci.muni.cz\/ofiz\/en\/danio-rerio-embryos-in-research-%f0%9f%90%9f\/\",\"name\":\"Danio rerio embryos in research \ud83d\udc1f - 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