{"id":3224,"date":"2019-10-21T07:12:28","date_gmt":"2019-10-21T07:12:28","guid":{"rendered":"http:\/\/www.sci.muni.cz\/ofiz\/?p=3224"},"modified":"2019-10-22T09:41:47","modified_gmt":"2019-10-22T09:41:47","slug":"getting-out-of-an-egg-merging-of-tooth-germs-to-create-an-egg-tooth-in-the-snake-2","status":"publish","type":"post","link":"https:\/\/ueb1.sci.muni.cz\/ofiz\/en\/getting-out-of-an-egg-merging-of-tooth-germs-to-create-an-egg-tooth-in-the-snake-2\/","title":{"rendered":"Getting out of an egg: Merging of tooth germs to create an egg tooth in the snake"},"content":{"rendered":"\n<h4 class=\"wp-block-heading\">BACKGROUND: <\/h4>\n\n\n\n<p>The egg tooth is a vital structure allowing hatchlings to escape from the egg. In squamates (snakes and lizards),  the egg tooth is a real tooth that develops within the oral cavity at the top of the upper jaw. Most squamates have a single large midline egg tooth at hatching, but a few families, such as Gekkonidae, have two egg teeth. In<g class=\"gr_ gr_7 gr-alert gr_gramm gr_inline_cards gr_run_anim Punctuation only-ins replaceWithoutSep gr-progress sel\" id=\"7\" data-gr-id=\"7\"> <\/g>snakes the egg tooth is significantly larger than the rest of the dentition and is one of the first teeth to develop.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">RESULTS: <\/h4>\n\n\n\n<p>We follow the development of the egg tooth in four snake species and show that the single egg tooth is formed by two tooth germs. These two tooth germs are united at the midline and grow together to produce a single tooth. In culture, this merging can be perturbed to give rise to separate smaller teeth, confirming the potential of the developing egg tooth to form two teeth.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">CONCLUSIONS: <\/h4>\n\n\n\n<p>Our data agree with previous hypotheses that during evolution one potential mechanism to generate a large tooth is through <g class=\"gr_ gr_3 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling ins-del multiReplace\" id=\"3\" data-gr-id=\"3\"><g class=\"gr_ gr_3 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling ins-del multiReplace\" id=\"3\" data-gr-id=\"3\">congrescence<\/g><\/g> of multiple tooth germs and suggests that the ancestors of snakes could have had two egg teeth.<\/p>\n\n\n\n<p>Read the whole story: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31587402\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31587402<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>BACKGROUND: The egg tooth is a vital structure allowing hatchlings to escape from the egg. In squamates (snakes and lizards), the egg tooth is a real tooth that develops within the oral cavity at the top of the upper jaw. &hellip; <a href=\"https:\/\/ueb1.sci.muni.cz\/ofiz\/en\/getting-out-of-an-egg-merging-of-tooth-germs-to-create-an-egg-tooth-in-the-snake-2\/\">Read More<\/a><\/p>\n","protected":false},"author":5,"featured_media":3222,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"kt_blocks_editor_width":"","_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[256],"tags":[322],"class_list":["post-3224","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-new-paper","tag-buchtova-lab-en"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.1.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Getting out of an egg: Merging of tooth germs to create an egg tooth in the snake - Department of Animal Physiology and Immunology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ueb1.sci.muni.cz\/ofiz\/en\/getting-out-of-an-egg-merging-of-tooth-germs-to-create-an-egg-tooth-in-the-snake-2\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Getting out of an egg: Merging of tooth germs to create an egg tooth in the snake - Department of Animal Physiology and Immunology\" \/>\n<meta property=\"og:description\" content=\"BACKGROUND: The egg tooth is a vital structure allowing hatchlings to escape from the egg. In squamates (snakes and lizards), the egg tooth is a real tooth that develops within the oral cavity at the top of the upper jaw. &hellip; Read More\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ueb1.sci.muni.cz\/ofiz\/en\/getting-out-of-an-egg-merging-of-tooth-germs-to-create-an-egg-tooth-in-the-snake-2\/\" \/>\n<meta property=\"og:site_name\" content=\"Department of Animal Physiology and Immunology\" \/>\n<meta property=\"article:published_time\" content=\"2019-10-21T07:12:28+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2019-10-22T09:41:47+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ueb1.sci.muni.cz\/ofiz\/wp-content\/uploads\/2019\/10\/P_20191021.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"854\" \/>\n\t<meta property=\"og:image:height\" content=\"572\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Lucie Nesvadbov\u00e1\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Lucie Nesvadbov\u00e1\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/ueb1.sci.muni.cz\/ofiz\/en\/getting-out-of-an-egg-merging-of-tooth-germs-to-create-an-egg-tooth-in-the-snake-2\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/ueb1.sci.muni.cz\/ofiz\/en\/getting-out-of-an-egg-merging-of-tooth-germs-to-create-an-egg-tooth-in-the-snake-2\/\"},\"author\":{\"name\":\"Lucie Nesvadbov\u00e1\",\"@id\":\"https:\/\/ueb1.sci.muni.cz\/ofiz\/#\/schema\/person\/3119766c8e4c78f08bbbde220469aee6\"},\"headline\":\"Getting out of an egg: Merging of tooth germs to create an egg tooth in the snake\",\"datePublished\":\"2019-10-21T07:12:28+00:00\",\"dateModified\":\"2019-10-22T09:41:47+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/ueb1.sci.muni.cz\/ofiz\/en\/getting-out-of-an-egg-merging-of-tooth-germs-to-create-an-egg-tooth-in-the-snake-2\/\"},\"wordCount\":220,\"publisher\":{\"@id\":\"https:\/\/ueb1.sci.muni.cz\/ofiz\/#organization\"},\"image\":{\"@id\":\"https:\/\/ueb1.sci.muni.cz\/ofiz\/en\/getting-out-of-an-egg-merging-of-tooth-germs-to-create-an-egg-tooth-in-the-snake-2\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/ueb1.sci.muni.cz\/ofiz\/wp-content\/uploads\/2019\/10\/P_20191021.jpg\",\"keywords\":[\"Buchtova Lab-EN\"],\"articleSection\":[\"New paper\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/ueb1.sci.muni.cz\/ofiz\/en\/getting-out-of-an-egg-merging-of-tooth-germs-to-create-an-egg-tooth-in-the-snake-2\/\",\"url\":\"https:\/\/ueb1.sci.muni.cz\/ofiz\/en\/getting-out-of-an-egg-merging-of-tooth-germs-to-create-an-egg-tooth-in-the-snake-2\/\",\"name\":\"Getting out of an egg: Merging of tooth germs to create an egg tooth in the snake - 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